RanBP9 overexpression reduces dendritic arbor and spine density
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چکیده
منابع مشابه
RanBP9 overexpression reduces dendritic arbor and spine density
RanBP9 is a multi-domain scaffolding protein known to integrate extracellular signaling with intracellular targets. We previously demonstrated that RanBP9 enhances Aβ generation and amyloid plaque burden which results in loss of specific pre- and postsynaptic proteins in vivo in a transgenic mouse model. Additionally, we showed that the levels of spinophilin, a marker of dendritic spines were i...
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ژورنال
عنوان ژورنال: Neuroscience
سال: 2014
ISSN: 0306-4522
DOI: 10.1016/j.neuroscience.2014.01.045